Expression of a mutated bovine growth hormone gene suppresses growth of transgenic mice.
To determine the importance of the third alpha-helix in bovine growth hormone (bGH) relative to growth-related biological activities, the following experimental approach was used: (i) mutagenesis of helix III of bGH to generate an idealized amphiphilic helix; (ii) in vitro expression analyses of the...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54261/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2367524/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.13.5061 |
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