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Heterologous introns can enhance expression of transgenes in mice.

In a previous study we showed that genomic constructs were expressed more efficiently in transgenic mice than constructs that were identical except for the lack of introns. Using the mouse metallothionein promoter-rat growth hormone gene construct as a model, we show that the first intron of the rat...

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Détails bibliographiques
Auteurs principaux: Palmiter, R D, Sandgren, E P, Avarbock, M R, Allen, D D, Brinster, R L
Format: Artigo
Langue:Inglês
Publié: 1991
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC50834/
https://ncbi.nlm.nih.gov/pubmed/1988947
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