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B cell depletion promotes aortic infiltration of immunosuppressive cells and is protective of experimental aortic aneurysm

OBJECTIVE: B cell depletion therapy is widely used for treatment of cancers and autoimmune diseases. B cells are abundant in abdominal aortic aneurysms (AAA), however, it is unknown whether B cell depletion therapy affects AAA growth. Using experimental models of murine AAA, we aim to examine the ef...

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Dades bibliogràfiques
Publicat a:Arterioscler Thromb Vasc Biol
Autors principals: Schaheen, Basil, Downs, Emily A., Serbulea, Vlad, Almenara, Camila C.P., Spinosa, Michael, Su, Gang, Zhao, Yunge, Srikakulapu, Prasad, Butts, Cherié, McNamara, Coleen A., Leitinger, Norbert, Upchurch, Gilbert R., Meher, Akshaya K., Ailawadi, Gorav
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083246/
https://ncbi.nlm.nih.gov/pubmed/27634836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307559
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