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Pharmacologic Blockade and Genetic Deletion of Androgen Receptor Attenuates Aortic Aneurysm Formation

BACKGROUND: Testosterone is theorized to play a major role in the pathophysiology of abdominal aortic aneurysms (AAAs) as this disease occurs primarily in males. The role of the androgen receptor (AR) in the formation of AAAs has not been well elucidated and therefore it is hypothesized that androge...

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Detalhes bibliográficos
Publicado no:J Vasc Surg
Main Authors: Davis, John P., Salmon, Morgan, Pope, Nicolas H., Lu, Guanyi, Su, Gang, Meher, Akshaya, Ailawadi, Gorav, Upchurch, Gilbert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884130/
https://ncbi.nlm.nih.gov/pubmed/26817611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2015.11.038
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