Pharmacologic Blockade and Genetic Deletion of Androgen Receptor Attenuates Aortic Aneurysm Formation

BACKGROUND: Testosterone is theorized to play a major role in the pathophysiology of abdominal aortic aneurysms (AAAs) as this disease occurs primarily in males. The role of the androgen receptor (AR) in the formation of AAAs has not been well elucidated and therefore it is hypothesized that androge...

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Опубликовано в: :J Vasc Surg
Главные авторы: Davis, John P., Salmon, Morgan, Pope, Nicolas H., Lu, Guanyi, Su, Gang, Meher, Akshaya, Ailawadi, Gorav, Upchurch, Gilbert R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884130/
https://ncbi.nlm.nih.gov/pubmed/26817611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2015.11.038
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