B cell depletion promotes aortic infiltration of immunosuppressive cells and is protective of experimental aortic aneurysm

OBJECTIVE: B cell depletion therapy is widely used for treatment of cancers and autoimmune diseases. B cells are abundant in abdominal aortic aneurysms (AAA), however, it is unknown whether B cell depletion therapy affects AAA growth. Using experimental models of murine AAA, we aim to examine the ef...

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Publicado en:Arterioscler Thromb Vasc Biol
Autores principales: Schaheen, Basil, Downs, Emily A., Serbulea, Vlad, Almenara, Camila C.P., Spinosa, Michael, Su, Gang, Zhao, Yunge, Srikakulapu, Prasad, Butts, Cherié, McNamara, Coleen A., Leitinger, Norbert, Upchurch, Gilbert R., Meher, Akshaya K., Ailawadi, Gorav
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083246/
https://ncbi.nlm.nih.gov/pubmed/27634836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307559
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