Mast cell tryptase regulates rat colonic myocytes through proteinase-activated receptor 2.

Proteinase-activated receptor-2 (PAR-2) is a G protein-coupled receptor that is cleaved and activated by trypsin-like enzymes. PAR-2 is highly expressed by small intestinal enterocytes where it is activated by luminal trypsin. The location, mechanism of activation, and biological functions of PAR-2...

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Hauptverfasser: Corvera, C U, Déry, O, McConalogue, K, Böhm, S K, Khitin, L M, Caughey, G H, Payan, D G, Bunnett, N W
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC508316/
https://ncbi.nlm.nih.gov/pubmed/9294103
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