Thrombin and mast cell tryptase regulate guinea-pig myenteric neurons through proteinase-activated receptors-1 and −2

1. Proteases regulate cells by cleaving proteinase-activated receptors (PARs). Thrombin and trypsin cleave PAR-1 and PAR-2 on neurons and astrocytes of the brain to regulate morphology, growth and survival. We hypothesized that thrombin and mast cell tryptase, which are generated and released during...

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Detalhes bibliográficos
Main Authors: Corvera, Carlos U, Déry, Olivier, McConalogue, Karen, Gamp, Patrick, Thoma, Mark, Al-Ani, Bahjat, Caughey, George H, Hollenberg, Morley D, Bunnett, Nigel W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269379/
https://ncbi.nlm.nih.gov/pubmed/10358115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.0741s.x
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