Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2

Proteinase-activated receptor 2 (PAR-2) is a recently characterized G-protein coupled receptor that is cleaved and activated by pancreatic trypsin. Trypsin is usually considered a digestive enzyme in the intestinal lumen. We examined the hypothesis that trypsin, at concentrations normally present in...

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Главные авторы: Kong, Wuyi, McConalogue, Karen, Khitin, Lev M., Hollenberg, Morley D., Payan, Donald G., Böhm, Stephan K., Bunnett, Nigel W.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences of the USA 1997
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC23180/
https://ncbi.nlm.nih.gov/pubmed/9238072
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