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Luminal trypsin may regulate enterocytes through proteinase-activated receptor 2

Proteinase-activated receptor 2 (PAR-2) is a recently characterized G-protein coupled receptor that is cleaved and activated by pancreatic trypsin. Trypsin is usually considered a digestive enzyme in the intestinal lumen. We examined the hypothesis that trypsin, at concentrations normally present in...

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Detalhes bibliográficos
Main Authors: Kong, Wuyi, McConalogue, Karen, Khitin, Lev M., Hollenberg, Morley D., Payan, Donald G., Böhm, Stephan K., Bunnett, Nigel W.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23180/
https://ncbi.nlm.nih.gov/pubmed/9238072
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