Mast cell tryptase and proteinase-activated receptor 2 induce hyperexcitability of guinea-pig submucosal neurons

Mast cells that are in close proximity to autonomic and enteric nerves release several mediators that cause neuronal hyperexcitability. This study examined whether mast cell tryptase evokes acute and long-term hyperexcitability in submucosal neurons from the guinea-pig ileum by activating proteinase...

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Bibliografiske detaljer
Main Authors: Reed, David E, Barajas-Lopez, Carlos, Cottrell, Graeme, Velazquez-Rocha, Sara, Dery, Olivier, Grady, Eileen F, Bunnett, Nigel W, Vanner, Stephen J
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2003
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342663/
https://ncbi.nlm.nih.gov/pubmed/12562962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.032011
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