Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior

Mutations in MECP2 cause the neurodevelopmental disorder Rett syndrome (RTT). The RTT missense MECP2(R306C) mutation prevents MeCP2 interaction with NCoR/Histone deacetylase 3 (HDAC3); however, the neuronal function of HDAC3 is incompletely understood. We report that neuronal deletion of Hdac3 in mi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Neurosci
Autors principals: Nott, Alexi, Cheng, Jemmie, Gao, Fan, Lin, Yuan-Ta, Gjoneska, Elizabeta, Ko, Tak, Minhas, Paras, Zamudio, Alicia Viridiana, Meng, Jia, Zhang, Feiran, Jin, Peng, Tsai, Li-Huei
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083138/
https://ncbi.nlm.nih.gov/pubmed/27428650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4347
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars