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Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior
Mutations in MECP2 cause the neurodevelopmental disorder Rett syndrome (RTT). The RTT missense MECP2(R306C) mutation prevents MeCP2 interaction with NCoR/Histone deacetylase 3 (HDAC3); however, the neuronal function of HDAC3 is incompletely understood. We report that neuronal deletion of Hdac3 in mi...
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| Veröffentlicht in: | Nat Neurosci |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5083138/ https://ncbi.nlm.nih.gov/pubmed/27428650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4347 |
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