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Phosphorylated human tau associates with mouse prion protein amyloid in scrapie-infected mice but does not increase progression of clinical disease

Tauopathies are a family of neurodegenerative diseases in which fibrils of human hyperphosphorylated tau (P-tau) are believed to cause neuropathology. In Alzheimer disease, P-tau associates with A-beta amyloid and contributes to disease pathogenesis. In familial human prion diseases and variant CJD,...

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Bibliografiske detaljer
Udgivet i:Prion
Main Authors: Race, Brent, Phillips, Katie, Kraus, Allison, Chesebro, Bruce
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082963/
https://ncbi.nlm.nih.gov/pubmed/27463540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2016.1199313
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