The mitogen-activated protein kinase pathway can mediate growth inhibition and proliferation in smooth muscle cells. Dependence on the availability of downstream targets.

Activation of the classical mitogen-activated protein kinase (MAPK) pathway leads to proliferation of many cell types. Accordingly, an inhibitor of MAPK kinase, PD 098059, inhibits PDGF-induced proliferation of human arterial smooth muscle cells (SMCs) that do not secrete growth-inhibitory PGs such...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Bornfeldt, K E, Campbell, J S, Koyama, H, Argast, G M, Leslie, C C, Raines, E W, Krebs, E G, Ross, R
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC508260/
https://ncbi.nlm.nih.gov/pubmed/9259587
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires