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Reduced Hsp70 and Glutamine in Pediatric Severe Malaria Anemia: Role of Hemozoin in Suppressing Hsp70 and NF-κB Activation

Severe malarial anemia (SMA; hemoglobin [Hb] <5.0 g/dL) is a leading global cause of morbidity and mortality among children residing in Plasmodium falciparum transmission regions. Exploration of molecular pathways through global gene expression profiling revealed that SMA was characterized by dec...

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Bibliografske podrobnosti
izdano v:Mol Med
Main Authors: Kempaiah, Prakasha, Dokladny, Karol, Karim, Zachary, Raballah, Evans, Ong’echa, John M, Moseley, Pope L, Perkins, Douglas J
Format: Artigo
Jezik:Inglês
Izdano: Feinstein Institute for Medical Research 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082292/
https://ncbi.nlm.nih.gov/pubmed/27579474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00130
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