Reduced Hsp70 and Glutamine in Pediatric Severe Malaria Anemia: Role of Hemozoin in Suppressing Hsp70 and NF-κB Activation

Severe malarial anemia (SMA; hemoglobin [Hb] <5.0 g/dL) is a leading global cause of morbidity and mortality among children residing in Plasmodium falciparum transmission regions. Exploration of molecular pathways through global gene expression profiling revealed that SMA was characterized by dec...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Kempaiah, Prakasha, Dokladny, Karol, Karim, Zachary, Raballah, Evans, Ong’echa, John M, Moseley, Pope L, Perkins, Douglas J
Formato: Artigo
Idioma:Inglês
Publicado em: Feinstein Institute for Medical Research 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082292/
https://ncbi.nlm.nih.gov/pubmed/27579474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00130
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