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Aldehyde Dehydrogenase 2 in Aplastic Anemia, Fanconi Anemia and Hematopoietic Stem Cells

Maintenance of the hematopoietic stem cell (HSC) compartment depends on the ability to metabolize exogenously and endogenously generated toxins, and to repair cellular damage caused by such toxins. Reactive aldehydes have been demonstrated to cause specific genotoxic injury, namely DNA interstrand c...

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Bibliografski detalji
Izdano u:Mol Genet Metab
Glavni autori: Van Wassenhove, Lauren D., Mochly-Rosen, Daria, Weinberg, Kenneth I.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082284/
https://ncbi.nlm.nih.gov/pubmed/27650066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2016.07.004
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