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Aldehyde Dehydrogenase 2 in Aplastic Anemia, Fanconi Anemia and Hematopoietic Stem Cells

Maintenance of the hematopoietic stem cell (HSC) compartment depends on the ability to metabolize exogenously and endogenously generated toxins, and to repair cellular damage caused by such toxins. Reactive aldehydes have been demonstrated to cause specific genotoxic injury, namely DNA interstrand c...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Genet Metab
मुख्य लेखकों: Van Wassenhove, Lauren D., Mochly-Rosen, Daria, Weinberg, Kenneth I.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082284/
https://ncbi.nlm.nih.gov/pubmed/27650066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2016.07.004
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