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Aldehyde Dehydrogenase 2 in Aplastic Anemia, Fanconi Anemia and Hematopoietic Stem Cells

Maintenance of the hematopoietic stem cell (HSC) compartment depends on the ability to metabolize exogenously and endogenously generated toxins, and to repair cellular damage caused by such toxins. Reactive aldehydes have been demonstrated to cause specific genotoxic injury, namely DNA interstrand c...

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Detaylı Bibliyografya
Yayımlandı:Mol Genet Metab
Asıl Yazarlar: Van Wassenhove, Lauren D., Mochly-Rosen, Daria, Weinberg, Kenneth I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082284/
https://ncbi.nlm.nih.gov/pubmed/27650066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2016.07.004
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