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Exploring the aggregation free energy landscape of the amyloid-β protein (1–40)

A predictive coarse-grained protein force field [associative memory, water-mediated, structure, and energy model for molecular dynamics (AWSEM)-MD] is used to study the energy landscapes and relative stabilities of amyloid-β protein (1–40) in the monomer and all of its oligomeric forms up to an octa...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Zheng, Weihua, Tsai, Min-Yeh, Chen, Mingchen, Wolynes, Peter G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081630/
https://ncbi.nlm.nih.gov/pubmed/27698130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612362113
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