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Stimulating S-adenosyl-l-methionine synthesis extends lifespan via activation of AMPK
Dietary restriction (DR), such as calorie restriction (CR) or methionine (Met) restriction, extends the lifespan of diverse model organisms. Although studies have identified several metabolites that contribute to the beneficial effects of DR, the molecular mechanism underlying the key metabolites re...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5081624/ https://ncbi.nlm.nih.gov/pubmed/27698120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604047113 |
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