Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia

AIMS: Normalization of hypercholesterolaemia, inflammation, hyperglycaemia, and obesity are main desired targets to prevent cardiovascular clinical events. Here we present a novel regulator of cholesterol metabolism, which simultaneously impacts on glucose intolerance and inflammation. METHODS AND R...

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Publicado en:Eur Heart J
Autores principales: Marsch, Elke, Demandt, Jasper A.F., Theelen, Thomas L., Tullemans, Bibian M.E., Wouters, Kristiaan, Boon, Mariëtte R., van Dijk, Theo H., Gijbels, Marion J., Dubois, Ludwig J., Meex, Steven J.R., Mazzone, Massimiliano, Hung, Gene, Fisher, Edward A., Biessen, Erik A.L., Daemen, Mat J.A.P., Rensen, Patrick C.N., Carmeliet, Peter, Groen, Albert K., Sluimer, Judith C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
EHJ Brief Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081036/
https://ncbi.nlm.nih.gov/pubmed/27125949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehw156
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