Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia

AIMS: Normalization of hypercholesterolaemia, inflammation, hyperglycaemia, and obesity are main desired targets to prevent cardiovascular clinical events. Here we present a novel regulator of cholesterol metabolism, which simultaneously impacts on glucose intolerance and inflammation. METHODS AND R...

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Detalhes bibliográficos
Publicado no:Eur Heart J
Main Authors: Marsch, Elke, Demandt, Jasper A.F., Theelen, Thomas L., Tullemans, Bibian M.E., Wouters, Kristiaan, Boon, Mariëtte R., van Dijk, Theo H., Gijbels, Marion J., Dubois, Ludwig J., Meex, Steven J.R., Mazzone, Massimiliano, Hung, Gene, Fisher, Edward A., Biessen, Erik A.L., Daemen, Mat J.A.P., Rensen, Patrick C.N., Carmeliet, Peter, Groen, Albert K., Sluimer, Judith C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
EHJ Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081036/
https://ncbi.nlm.nih.gov/pubmed/27125949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehw156
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