Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells

Mesenchymal stromal cells (MSCs) are strongly immunosuppressive via producing nitric oxide (NO) and known to migrate into tumor sites to promote tumor growth, but the underlying mechanisms remain largely elusive. Here, we found that interferon alpha (IFNα)-secreting MSCs showed more dramatic inhibit...

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Detaylı Bibliyografya
Yayımlandı:Oncogene
Asıl Yazarlar: Shou, P, Chen, Q, Jiang, J, Xu, C, Zhang, J, Zheng, C, Jiang, M, Velletri, T, Cao, W, Huang, Y, Yang, Q, Han, X, Zhang, L, Wei, L, Rabson, A B, Chin, Y E, Wang, Y, Shi, Y
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079855/
https://ncbi.nlm.nih.gov/pubmed/27109100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.128
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