Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells

Mesenchymal stromal cells (MSCs) are strongly immunosuppressive via producing nitric oxide (NO) and known to migrate into tumor sites to promote tumor growth, but the underlying mechanisms remain largely elusive. Here, we found that interferon alpha (IFNα)-secreting MSCs showed more dramatic inhibit...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncogene
Main Authors: Shou, P, Chen, Q, Jiang, J, Xu, C, Zhang, J, Zheng, C, Jiang, M, Velletri, T, Cao, W, Huang, Y, Yang, Q, Han, X, Zhang, L, Wei, L, Rabson, A B, Chin, Y E, Wang, Y, Shi, Y
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079855/
https://ncbi.nlm.nih.gov/pubmed/27109100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.128
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