Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells

Mesenchymal stromal cells (MSCs) are strongly immunosuppressive via producing nitric oxide (NO) and known to migrate into tumor sites to promote tumor growth, but the underlying mechanisms remain largely elusive. Here, we found that interferon alpha (IFNα)-secreting MSCs showed more dramatic inhibit...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Shou, P, Chen, Q, Jiang, J, Xu, C, Zhang, J, Zheng, C, Jiang, M, Velletri, T, Cao, W, Huang, Y, Yang, Q, Han, X, Zhang, L, Wei, L, Rabson, A B, Chin, Y E, Wang, Y, Shi, Y
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079855/
https://ncbi.nlm.nih.gov/pubmed/27109100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.128
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