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Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells
Mesenchymal stromal cells (MSCs) are strongly immunosuppressive via producing nitric oxide (NO) and known to migrate into tumor sites to promote tumor growth, but the underlying mechanisms remain largely elusive. Here, we found that interferon alpha (IFNα)-secreting MSCs showed more dramatic inhibit...
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| Опубликовано в: : | Oncogene |
|---|---|
| Главные авторы: | , , , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5079855/ https://ncbi.nlm.nih.gov/pubmed/27109100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.128 |
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