Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells

Mesenchymal stromal cells (MSCs) are strongly immunosuppressive via producing nitric oxide (NO) and known to migrate into tumor sites to promote tumor growth, but the underlying mechanisms remain largely elusive. Here, we found that interferon alpha (IFNα)-secreting MSCs showed more dramatic inhibit...

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Опубликовано в: :Oncogene
Главные авторы: Shou, P, Chen, Q, Jiang, J, Xu, C, Zhang, J, Zheng, C, Jiang, M, Velletri, T, Cao, W, Huang, Y, Yang, Q, Han, X, Zhang, L, Wei, L, Rabson, A B, Chin, Y E, Wang, Y, Shi, Y
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079855/
https://ncbi.nlm.nih.gov/pubmed/27109100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.128
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