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Design of Peptide and Peptidomimetic Ligands with Novel Pharmacological Activity Profiles

Peptide hormones and neurotransmitters are of central importance in most aspects of intercellular communication and are involved in virtually all degenerative diseases. In this review, we discuss physicochemical approaches to the design of novel peptide and peptidomimetic agonists, antagonists, inve...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Annu Rev Pharmacol Toxicol
Hauptverfasser: Hruby, Victor J., Cai, Minying
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079645/
https://ncbi.nlm.nih.gov/pubmed/23294313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010510-100456
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