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Design of Peptide and Peptidomimetic Ligands with Novel Pharmacological Activity Profiles

Peptide hormones and neurotransmitters are of central importance in most aspects of intercellular communication and are involved in virtually all degenerative diseases. In this review, we discuss physicochemical approaches to the design of novel peptide and peptidomimetic agonists, antagonists, inve...

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Detalhes bibliográficos
Publicado no:Annu Rev Pharmacol Toxicol
Main Authors: Hruby, Victor J., Cai, Minying
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079645/
https://ncbi.nlm.nih.gov/pubmed/23294313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010510-100456
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