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Design of Peptide and Peptidomimetic Ligands with Novel Pharmacological Activity Profiles

Peptide hormones and neurotransmitters are of central importance in most aspects of intercellular communication and are involved in virtually all degenerative diseases. In this review, we discuss physicochemical approaches to the design of novel peptide and peptidomimetic agonists, antagonists, inve...

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Détails bibliographiques
Publié dans:Annu Rev Pharmacol Toxicol
Auteurs principaux: Hruby, Victor J., Cai, Minying
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079645/
https://ncbi.nlm.nih.gov/pubmed/23294313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010510-100456
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