טוען...
Exploration of the conformational landscape in pregnane X receptor reveals a new binding pocket
Ligand‐regulated pregnane X receptor (PXR), a member of the nuclear receptor superfamily, plays a central role in xenobiotic metabolism. Despite its critical role in drug metabolism, PXR activation can lead to adverse drug‐drug interactions and early stage metabolism of drugs. Activated PXR can indu...
שמור ב:
| הוצא לאור ב: | Protein Sci |
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| Main Authors: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
John Wiley and Sons Inc.
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5079256/ https://ncbi.nlm.nih.gov/pubmed/27515410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3012 |
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