Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice.

A new mouse cardiac electrophysiology method was used to study mice harboring an alpha-myosin heavy chain Arg403Gln missense mutation (alpha-MHC403/+), which results in histological and hemodynamic abnormalities characteristic of familial hypertrophic cardiomyopathy (FHC) and sudden death of uncerta...

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Pubblicato in:	J Clin Invest
Autori principali:	Berul, C I, Christe, M E, Aronovitz, M J, Seidman, C E, Seidman, J G, Mendelsohn, M E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507836/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9045856/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119197
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