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Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice.

A new mouse cardiac electrophysiology method was used to study mice harboring an alpha-myosin heavy chain Arg403Gln missense mutation (alpha-MHC403/+), which results in histological and hemodynamic abnormalities characteristic of familial hypertrophic cardiomyopathy (FHC) and sudden death of uncerta...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Berul, C I, Christe, M E, Aronovitz, M J, Seidman, C E, Seidman, J G, Mendelsohn, M E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507836/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9045856/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119197
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