Epidermal Growth Factor Receptor Signaling Regulates β Cell Proliferation in Adult Mice

A thorough understanding of the signaling pathways involved in the regulation of β cell proliferation is an important initial step in restoring β cell mass in the diabetic patient. Here, we show that epidermal growth factor receptor 1 (EGFR) was significantly up-regulated in the islets of C57BL/6 mi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Song, Zewen, Fusco, Joseph, Zimmerman, Ray, Fischbach, Shane, Chen, Congde, Ricks, David Matthew, Prasadan, Krishna, Shiota, Chiyo, Xiao, Xiangwei, Gittes, George K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077199/
https://ncbi.nlm.nih.gov/pubmed/27587395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.747840
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