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Transient Suppression of TGFβ Receptor Signaling Facilitates Human Islet Transplantation

Although islet transplantation is an effective treatment for severe diabetes, its broad application is greatly limited due to a shortage of donor islets. Suppression of TGFβ receptor signaling in β-cells has been shown to increase β-cell proliferation in mice, but has not been rigorously examined in...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Xiao, Xiangwei, Fischbach, Shane, Song, Zewen, Gaffar, Iljana, Zimmerman, Ray, Wiersch, John, Prasadan, Krishna, Shiota, Chiyo, Guo, Ping, Ramachandran, Sabarinathan, Witkowski, Piotr, Gittes, George K.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816736/
https://ncbi.nlm.nih.gov/pubmed/26872091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1986
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