Molecular Architecture of Full-length TRF1 Favors Its Interaction with DNA

Telomeres are specific DNA-protein structures found at both ends of eukaryotic chromosomes that protect the genome from degradation and from being recognized as double-stranded breaks. In vertebrates, telomeres are composed of tandem repeats of the TTAGGG sequence that are bound by a six-subunit com...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Boskovic, Jasminka, Martinez-Gago, Jaime, Mendez-Pertuz, Marinela, Buscato, Alberto, Martinez-Torrecuadrada, Jorge Luis, Blasco, Maria A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
DNA and Chromosomes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076849/
https://ncbi.nlm.nih.gov/pubmed/27563064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.744896
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