BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy

Mutations in PINK1 (PTEN-induced putative kinase 1) cause early onset familial Parkinson's disease (PD). PINK1 accumulates on the outer membrane of damaged mitochondria followed by recruiting parkin to promote mitophagy. Here, we demonstrate that BCL2/adenovirus E1B 19-kDa interacting protein 3...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Zhang, Tongmei, Xue, Liang, Li, Li, Tang, Chengyuan, Wan, Zhengqing, Wang, Ruoxi, Tan, Jieqiong, Tan, Ya, Han, Hailong, Tian, Runyi, Billiar, Timothy R., Tao, W. Andy, Zhang, Zhuohua
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076832/
https://ncbi.nlm.nih.gov/pubmed/27528605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.733410
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars