Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases

SgK269/PEAK1 is a pseudokinase and scaffolding protein that plays a critical role in regulating growth factor receptor signal output and is implicated in the progression of several cancers, including those of the breast, colon, and pancreas. SgK269 is structurally related to SgK223, a human pseudoki...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Liu, Ling, Phua, Yu Wei, Lee, Rachel S., Ma, Xiuquan, Jenkins, Yiping, Novy, Karel, Humphrey, Emily S., Chan, Howard, Shearer, Robert, Ong, Poh Chee, Dai, Weiwen, Saunders, Darren N., Lucet, Isabelle S., Daly, Roger J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076828/
https://ncbi.nlm.nih.gov/pubmed/27531744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.748897
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