Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases

SgK269/PEAK1 is a pseudokinase and scaffolding protein that plays a critical role in regulating growth factor receptor signal output and is implicated in the progression of several cancers, including those of the breast, colon, and pancreas. SgK269 is structurally related to SgK223, a human pseudoki...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Liu, Ling, Phua, Yu Wei, Lee, Rachel S., Ma, Xiuquan, Jenkins, Yiping, Novy, Karel, Humphrey, Emily S., Chan, Howard, Shearer, Robert, Ong, Poh Chee, Dai, Weiwen, Saunders, Darren N., Lucet, Isabelle S., Daly, Roger J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076828/
https://ncbi.nlm.nih.gov/pubmed/27531744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.748897
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