5′ to 3′ Unfolding Directionality of DNA Secondary Structures by Replication Protein A: G-QUADRUPLEXES AND DUPLEXES

The replication protein A (RPA) is a single-stranded DNA-binding protein that plays an essential role in DNA metabolism. RPA is able to unfold G-quadruplex (G4) structures formed by telomeric DNA sequences, a function important for telomere maintenance. To elucidate the mechanism through which RPA u...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Safa, Layal, Gueddouda, Nassima Meriem, Thiébaut, Frédéric, Delagoutte, Emmanuelle, Petruseva, Irina, Lavrik, Olga, Mendoza, Oscar, Bourdoncle, Anne, Alberti, Patrizia, Riou, Jean-François, Saintomé, Carole
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Molecular Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076531/
https://ncbi.nlm.nih.gov/pubmed/27440048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.709667
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