Chargement en cours...

A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands

Helicases, enzymes that unwind DNA or RNA structure, are present in the cell nucleus and in the mitochondrion. Although the majority of the helicases unwind DNA or RNA duplexes, some of these proteins are known to resolve unusual structures such as G-quadruplexes (G4) in vitro. G4 may form stable ba...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Mendoza, Oscar, Gueddouda, Nassima Meriem, Boulé, Jean-Baptiste, Bourdoncle, Anne, Mergny, Jean-Louis
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477640/
https://ncbi.nlm.nih.gov/pubmed/25765657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv193
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!