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A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands
Helicases, enzymes that unwind DNA or RNA structure, are present in the cell nucleus and in the mitochondrion. Although the majority of the helicases unwind DNA or RNA duplexes, some of these proteins are known to resolve unusual structures such as G-quadruplexes (G4) in vitro. G4 may form stable ba...
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| Foilsithe in: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Oxford University Press
2015
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4477640/ https://ncbi.nlm.nih.gov/pubmed/25765657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv193 |
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