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A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands

Helicases, enzymes that unwind DNA or RNA structure, are present in the cell nucleus and in the mitochondrion. Although the majority of the helicases unwind DNA or RNA duplexes, some of these proteins are known to resolve unusual structures such as G-quadruplexes (G4) in vitro. G4 may form stable ba...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Mendoza, Oscar, Gueddouda, Nassima Meriem, Boulé, Jean-Baptiste, Bourdoncle, Anne, Mergny, Jean-Louis
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477640/
https://ncbi.nlm.nih.gov/pubmed/25765657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv193
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