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A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands
Helicases, enzymes that unwind DNA or RNA structure, are present in the cell nucleus and in the mitochondrion. Although the majority of the helicases unwind DNA or RNA duplexes, some of these proteins are known to resolve unusual structures such as G-quadruplexes (G4) in vitro. G4 may form stable ba...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4477640/ https://ncbi.nlm.nih.gov/pubmed/25765657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv193 |
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