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Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice.

The finding that intracellular expression of the beta-amyloid protein (Abeta) under a neuron-specific promoter led progressively to degeneration and death of neurons in the brains of transgenic mice provides a unique opportunity to utilize this animal model to both understand the mechanism that unde...

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Bibliografski detalji
Glavni autori: LaFerla, F M, Hall, C K, Ngo, L, Jay, G
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC507596/
https://ncbi.nlm.nih.gov/pubmed/8833912
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