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Cell resistance to the Cytolethal Distending Toxin involves an association of DNA repair mechanisms
The Cytolethal Distending Toxin (CDT), produced by many bacteria, has been associated with various diseases including cancer. CDT induces DNA double-strand breaks (DSBs), leading to cell death or mutagenesis if misrepaired. At low doses of CDT, other DNA lesions precede replication-dependent DSB for...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5075911/ https://ncbi.nlm.nih.gov/pubmed/27775089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36022 |
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