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The Cytolethal Distending Toxin Effects on Mammalian Cells: A DNA Damage Perspective
The cytolethal distending toxin (CDT) is produced by many pathogenic Gram-negative bacteria and is considered as a virulence factor. In human cells, CDT exposure leads to a unique cytotoxicity associated with a characteristic cell distension and induces a cell cycle arrest dependent on the DNA damag...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4092857/ https://ncbi.nlm.nih.gov/pubmed/24921185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells3020592 |
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