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The Cytolethal Distending Toxin Effects on Mammalian Cells: A DNA Damage Perspective

The cytolethal distending toxin (CDT) is produced by many pathogenic Gram-negative bacteria and is considered as a virulence factor. In human cells, CDT exposure leads to a unique cytotoxicity associated with a characteristic cell distension and induces a cell cycle arrest dependent on the DNA damag...

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Bibliografiske detaljer
Main Authors: Bezine, Elisabeth, Vignard, Julien, Mirey, Gladys
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4092857/
https://ncbi.nlm.nih.gov/pubmed/24921185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells3020592
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