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Antileishmanial Mechanism of Diamidines Involves Targeting Kinetoplasts

Leishmaniasis is a disease caused by pathogenic Leishmania parasites; current treatments are toxic and expensive, and drug resistance has emerged. While pentamidine, a diamidine-type compound, is one of the treatments, its antileishmanial mechanism of action has not been investigated in depth. Here...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Yang, Gyongseon, Choi, Gahee, No, Joo Hwan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075092/
https://ncbi.nlm.nih.gov/pubmed/27600039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01129-16
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