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Antileishmanial Effect of 3-Aminooxy-1-Aminopropane Is Due to Polyamine Depletion
The polyamines putrescine, spermidine, and spermine are organic cations that are required for cell growth and differentiation. Ornithine decarboxylase (ODC), the first and rate-limiting enzyme in the polyamine biosynthetic pathway, catalyzes the conversion of ornithine to putrescine. As the polyamin...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1797741/ https://ncbi.nlm.nih.gov/pubmed/17101681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01055-06 |
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