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Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities

New drugs are urgently needed for the treatment of tropical and subtropical parasitic diseases, such as African sleeping sickness, Chagas' disease, leishmaniasis and malaria. Enzymes in polyamine biosynthesis and thiol metabolism, as well as polyamine transporters, are potential drug targets wi...

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Detalhes bibliográficos
Main Authors: Birkholtz, Lyn-Marie, Williams, Marni, Niemand, Jandeli, Louw, Abraham I., Persson, Lo, Heby, Olle
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253432/
https://ncbi.nlm.nih.gov/pubmed/21834794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110362
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