Anthracene-Polyamine Conjugates Inhibit In Vitro Proliferation of Intraerythrocytic Plasmodium falciparum Parasites

Anthracene-polyamine conjugates inhibit the in vitro proliferation of the intraerythrocytic human malaria parasite Plasmodium falciparum, with 50% inhibitory concentrations (IC(50)s) in the nM to μM range. The compounds are taken up into the intraerythrocytic parasite, where they arrest the parasite...

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Detalhes bibliográficos
Main Authors: Niemand, Jandeli, Burger, Pieter, Verlinden, Bianca K., Reader, Janette, Joubert, Annie M., Kaiser, Annette, Louw, Abraham I., Kirk, Kiaran, Phanstiel, Otto, Birkholtz, Lyn-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716131/
https://ncbi.nlm.nih.gov/pubmed/23545535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00106-13
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